What is MOTS-c?
MOTS-c is a mitochondrial-derived peptide composed of 16 amino acids. It is encoded by mitochondrial DNA and is naturally present in human tissues. MOTS-c plays a significant role in cellular metabolism, energy regulation, and metabolic homeostasis.
Key Benefits
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Metabolic Regulation
- Enhances glucose uptake in skeletal muscle.
- Improves insulin sensitivity and supports healthy blood sugar levels.
- Promotes fatty acid oxidation and reduces fat accumulation.
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Weight Management
- May support weight loss by increasing energy expenditure and reducing fat storage.
- Shown in studies to reduce diet-induced obesity in animal models.
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Exercise Performance
- Increases endurance and physical performance by optimizing energy utilization.
- May reduce exercise-induced fatigue.
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Cellular Protection
- Protects cells from metabolic stress and oxidative damage.
- May have anti-inflammatory effects.
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Potential Anti-Aging Effects
- Supports mitochondrial function, which declines with age.
- May contribute to longevity and healthy aging in preclinical studies.


